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differential rheumatology abnormal clinical dermatology hemolytic pulmonary abnormalities agglutinin atlas autoimmune beaus breathing cold disease diseases dyspnea extravascular fingernails hemolysis
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Differential Diagnosis ... - Water - Pus ... Hepatopulmonary syndrome ... Transverse myelitis • Hematology ... : - Anemia •
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... ) - HELLP syndrome ... hemoglobinuria (PNH ... #hematology #anemia
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... - Hemolytic anemia ... Kasabach-Merritt syndrome ... deficiencies - PNH ... Gardner-Diamond syndrome
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... reticularis • Raynaud ... • Symptoms of anemia ... anemia • Cold ... #hematology #diagnosis
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN) Nikolsky's sign is a clinical dermatological sign which is present
Stevens-Johnson Syndrome ... , caused by the ... differentiating between the diagnosis ... #PhysicalExam # ... Video #Clinical
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 Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... - infiltrates (anemia ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... Cryoglobulinemia (4%-12%), Raynaud ... Diagnosis #Management
Abnormalities in Rate and Rhythm of Breathing Normal The respiratory rate is about 14—20 per min
the midbrain or pons ... heart failure, uremia ... hyperventilation syndrome—a ... Abnormalities #Abnormal #Diagnosis ... #PhysicalExam
Nail Pathologies - Findings in or Near Nails Paronychia A superficial infection of the proximal and lateral
include diabetes, anemia ... cold exposure if Raynaud's ... seen in Reiter's syndrome ... Abnormal #Pathology #Diagnosis ... Clinical #Signs #PhysicalExam
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... joint pain and Raynaud ... aspiration > 50% of pts ... • Myositis • Raynaud ... statins - probably caused
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