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diagnosis differential management rheumatology dermatology symptoms algorithm antinxp2 antinxp2dm arteritis autoimmune behcet brain cns dermatomyositis disease gca giantcell myelitis myopathy
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
CNS Ring-Enhancing ... + toxo IgG • CNS ... , may also see skin ... differential #diagnosis #causes ... #radiology #neurology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
response to local skin ... injury) • Neurologic ... test (this is a skin ... diagnosis #management #signs ... #symptoms #rheumatology
Papulosquamous Skin Rash - Differential Diagnosis Algorithm Erythrematous or violaceous papules & plaques with overlying scale •
Papulosquamous Skin ... Auspitz sign, Koebner's ... (Ring- shaped) lesion ... Papulosquamous #SkinRash ... Diagnosis #Algorithm #causes
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
lesions • Mononeuritis ... purpura: Strong sign ... , neurologic, and ... cognitive impairment, neurologic ... tract, and often causes
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... compressive cord lesion ... • Bilateral signs ... • Infectious causes ... diagnosis #management #neurology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... systemic sx + signs ... required due to skip ... lesions. ... GCA #Temporal #Signs
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
subcutaneous edema Pts ... chest (in a V-sign ... shoulders (in a shawl sign ... lesions: antihelix ... Muscle atrophy may cause
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... lesions) • Anti-TIF1 ... papules and Gottron sign ... ) • Shawl sign ... statins - probably caused
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