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diagnosis management dermatology rheumatology differential neurology syndrome antinxp2 antinxp2dm aplastic arteritis bee cutaneous dermatomyositis eschar gca giantcell mucormycosis myelitis noninflammatory
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... : - Genetic lesions ... Treatment: ... #oncology #hematology
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Non-inflammatory Causes ... nervous system (CNS ... diagnosis and treatment ... LHON) plus MRI lesions ... and clinical consistent
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Transverse Myelitis - Clinical ... compressive cord lesion ... or optic nerve lesions ... Transverse Myelitis Treatment
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... Pustular skin lesions ... Rheumatic pain Clinical ... Rule out other causes ... and lower jaw Treatment
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... systemic complaints- anemia ... required due to skip lesions ... of the steroid treatment ... Treatment of GCA
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK ... Adenocarcinoma Treatment
Cutaneous Mucormycosis Eschar 30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
immunosuppressed pts ... trauma, aplastic anemia ... from center of lesion ... Mucormycosis #Eschar #dermatology ... #skin #clinical
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
subcutaneous edema Pts ... Auricular skin lesions ... auricular papules Clinical ... Muscle atrophy may cause ... positive patients Treatment
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