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diagnosis differential thrombosis treatment algorithm anticoagulation arterial breakthrough intravascular venous vte anemia antinxp2 antinxp2dm cerebritis clots cns coagulation dermatomyositis dic
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework STRUCTURAL: - PFO: paradoxical emboli - Popliteal
Causes of Arterial ... compression and DVT ... endocarditis) - Disseminated ... neoplasms - PNH ... Diagnosis #clots #hematology
Recurrent / Breakthrough DVT During Anticoagulation Subtherapeutic Anticoagulation Hypercoagulable State - Antithrombin deficiency - Hypercoagulability ot
/ Breakthrough DVT ... APLS - MPN/PNH ... Structural - Pelvic masses ... Breakthrough #Recurrent #DVT ... anticoagulation #hematology
Causes of Breakthrough/Extension of Thrombosis and Management Algorithm #Anticoagulation #Breakthrough #Thrombosis #Algorithm #Extension #VTE #DVT #Hematology #Management
Causes of Breakthrough ... Thrombosis and Management ... Extension #VTE #DVT ... #Hematology #Management ... #Differential #Causes
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): - Disseminated ... hemoglobinuria (PNH ... Extravascular #Causes ... differential #diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... Treat primary cause ... bleeding #DIC #Disseminated ... #treatment #management ... #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... autoantibodies that will cause ... thrombosis and/or blood-brain ... #neurology #rheumatology ... cerebritis #diagnosis #management
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
considered in all cases ... thrombocytopenia - Disseminated ... coagulation and other causes ... - COVID-19 - PNH ... pathophysiology #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... Rule out other causes ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management ... #Dermatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
(depending on CNS ... steroids • In mild cases ... Options for severe cases ... HLH #Treatment #management ... #hematology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... MI, stroke, DVT/ ... Thrombocythemia #ET #hematology ... #diagnosis #management ... #hematology
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