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diagnosis anthracycline autoimmune cardiotoxicity chemotherapy differential her2 management mds myelodysplasia myelodysplastic myopathy myositis peripartum pharmacology rheumatology syndromes toxicity treatment
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... -> AML: Blast crises ... count ↑ PLT • ↑ PBS ... Transformation: • Complication ... #Hematology #Oncology
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
Peripartum Cardiomyopathy ... exclude other causes ... • Minority of Pts ... Thromboembolic complications ... diagnosis #management #cardiology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
carries a variable risk ... • Hairy Cell Leukemia ... and reducing the risk ... Syndromes #diagnosis #hematology ... #oncology
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity Anthracyclines cause cardiomyopathy: ✖ Reduction in left ventricular ejection fraction
Anthracyclines cause ... HER2 agents cause ... after 4 cycles for all ... Cardiotoxicity #cardiology ... #oncology #pharmacology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Polymyositis or ALS ... aspiration > 50% of pts ... statins - probably caused ... ) arrhythmias, cardiomyopathy ... Myositis #Myopathy #rheumatology
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