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diagnosis management syndrome rheumatology cll dermatology hemeonc lymphocytic mds myelodysplastic 1 algorithm alkaline alp anemia aplastic behcet brain cancer cardiomyopathy
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... with a relatively chronic ... -> AML: Blast crises ... Transformation: • Complication ... #Hematology #Oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... • Risks: infection ... transformation to acute leukemia ... only curative treatment ... #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... immunophenotype Clinical ... thrombocytopenia Complications ... chemotherapy for low-risk ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... organ damage Clinical ... Treat primary cause ... #treatment #management ... #hematology
Refeeding Syndrome Overview What Is It? • Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
severe clinical ... complications. ... Risk Factors: ... Malnutrition due to chronic ... hyperparathyroidism Treatment
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
GrepMed Handbook Clinical ... of hospitalized pts ... Spore ingestion → colonic ... Lowest Risk: Tetracyclines ... CT A/P: Assess complications
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
syndrome): - Hematologic ... mg/dL or > 25 % rise ... Treat underlying cause ... interventional radiology ... Usually myeloid leukemias
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Clinical • Under-recognized ... Thromboembolic complications ... diagnosis #management #cardiology ... #treatment
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
carries a variable risk ... Marrow Failure • Chronic ... Myelogenous Leukemia ... Syndromes #diagnosis #hematology ... #oncology
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