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management rheumatology dermatology differential syndrome infectiousdiseases algorithm leukemia workup activetb aspergillus cell chronic cll coccidioidomycosis comparison gastroenterology hemeonc idsa latenttb
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... and risk-stratification ... • Risks: infection ... #Management #treatment ... #hematology #oncology
Kerion Raised, boggy lesion with heaped up purulent nodules Caused by host's response to a fungal ringworm
purulent nodules Caused ... response to a fungal ... mentagrophytes) Clinical ... Lymphadenopathy Treatment ... #Diagnosis #Management
Candidemia Workup and Management - IDSA Guidelines 1) Antibiotics • Empiric: Echinocandins (e.g. micafungin) for most patients
Other hardware - Risk-Benefit ... or TEE unless clinical ... Consider: Spine, CNS ... #candidiasis #treatment ... #fungal #fungemia
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
infections are caused ... complex Classic Risk ... HIV/AIDS, CGD) Clinical ... #Management #treatment ... #fungal #infectiousdiseases
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Fungal Biomarkers ... infection (IFI) in hematologic ... cut-offs defined in clinical ... useful in high risk ... Galactomannan #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
immunophenotype Clinical ... thrombocytopenia Complications ... chemotherapy for low-risk ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... autoantibodies that will cause ... permeability Diagnosis ... #neurology #rheumatology ... #cerebritis #diagnosis
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Clinical • Under-recognized ... Thromboembolic complications ... #management #cardiology ... #treatment
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
> 4 days → add fungal ... syndrome): - Hematologic ... mg/dL or > 25 % rise ... Treat underlying cause ... #HemeOnc #Diagnosis
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
GrepMed Handbook Clinical ... of hospitalized pts ... Lowest Risk: Tetracyclines ... CT A/P: Assess complications ... KUB ↓↓Sens for complications
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