11 results
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Indications and Pharmacology ... , Post-partum, ICH ... Side Effects: Hypotension ... fatigue; Increases risk ... #hematology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
An acute rise or ... with previously stable ... and no other risk ... 109 mm Hg) with clinical ... apnea: CPAP, most pts
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
Clinically Significant ... increased bleed risk ... vera, Licorice - Causes ... supplementals #herbal #pharmacology ... #DDI #table #cardiology
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... heart disease • Hypertensive ... Avoid ARBs • ICD ... Thromboembolic complications ... diagnosis #management #cardiology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
transfused patientsl • Risk ... factors: Critical ... without other cause ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... and clinical associations ... shortness of breath, Hypotension ... Diagnostic tests - Ice ... #comparison #table
UCSF COVID-19 Adult Clinical Evaluation Guide - Updated April 10 2020

Clinical Presentation
• Fever: hospitalized pts but
: hospitalized pts ... Cardiac: multiple case ... % if severe or ICU ... 7-28% -> Incr risk ... complications,
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
the determined cause ... algorithm #management #cardiology ... #treatment #table ... #criticalcare #icu ... #clinical #pharmacology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... effusion, INC risk ... Nephrogenic DI Hematologic ... lubricants • Pharmacologic
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
syndrome): - Hematologic ... mg/dL or > 25 % rise ... Treat underlying cause ... rash, hypoxia, hypotension ... , weight gain, hypotension