14 results
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Iron deficiency anemia ... discoloration) • Chronic ... Muehrcke's Lines - Transverse ... #Secondary #dermatology ... Diagnosis #Algorithm #causes
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
and Primary Causes ... Creatinine & BUN: • Chronic ... renal failure/uremia ... #generalized #dermatology ... Diagnosis #Algorithm #causes
Erythema Ab Igne on Physical Exam

Erythema ab igne (EAI) is a skin reaction caused by chronic
igne (EAI) is a skin ... reaction caused ... by chronic heat ... #Igne #AbIgne #PhysicalExam ... #dermatology #rash
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... Amyloidosis (CVS+PNS ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
& Anti-La/SSB ab ... • Anti-Ro/SSA ab ... Hypocomplementemia • Can cause ... peripheral neuropathy, transverse ... Nephrogenic DI Hematologic
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
Summarized Erythema ab ... skin condition ... (cutaneous or systemic ... multiforme • Acute systemic ... differential #diagnosis #dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... - infiltrates (anemia ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
ANA, anti-Smith Ab ... 3rd Decade Skin ... neuropathy • Transverse ... lymphopenia, low PLT • Anemia ... with Lupus: • Chronic
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... Creatinine & BUN: • Chronic ... Pruritus #secondary #systemic ... #generalized #dermatology ... Diagnosis #Algorithm #causes
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Hepatomegaly • Skin ... • Neutropenia, anemia ... diagnosis #workup #oncology ... #hematology