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diagnosis differential algorithm oncology rheumatology systemic generalized management primary pruritus aplastic atlas basics clinical cryofibrinogenemia cutaneous dyspnea eschar key lesions
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Water - Pus ... Barre - ALS - Transverse ... myelitis • Hematology ... : - Anemia • ... #pulmonary
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Iron deficiency anemia ... Muehrcke's Lines - Transverse ... #dermatology #Differential ... Diagnosis #Algorithm #causes
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... leakage of RBC's secondary ... - Hemolytic anemia ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Systemic and Primary Causes ... renal failure/uremia ... Pruritus #primary #secondary ... #generalized #dermatology ... Diagnosis #Algorithm #causes
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
bone marrow + pancytopenia ... Headaches • Pale skin ... and petechiae Causes ... • Peripheral Pancytopenia ... #oncology #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Vascular reactivity (Skin ... thrombophlebitis, pulmonary ... cryoglobulins • Negative causes ... Warfarin-induced skin ... #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
other diseases • Secondary ... Hypocomplementemia • Can cause ... peripheral neuropathy, transverse ... , INC risk PE, Pulmonary ... Nephrogenic DI Hematologic
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... - infiltrates (anemia ... bone marrow and secondary ... CLL -> Invade Skin ... #Leukemia #Hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... renal failure/uremia ... #Pruritus #secondary ... #generalized #dermatology ... Diagnosis #Algorithm #causes
Primary Dermatological Lesions Primary lesions are physical changes in the skin considered to be caused directly by
considered to be caused ... associated with secondary ... features such as crusts ... lesions that contain pus ... #Diagnosis #Dermatology
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