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diagnosis rheumatology clinical management differential mri radiology syndrome arteritis brain crypto cryptococcal cutaneous dyspnea erythematosus eschar gca giantcell gout gouty
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Water - Pus ... Barre - ALS - Transverse ... myelitis • Hematology ... : - Anemia • ... Pain #dyspnea #sob
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... juvenile idiopathic arthritis ... nervous system (CNS ... with leukopenia, anemia ... Diagnosis #Management #Hematology
Gout (Gouty Arthritis) - MSK Radiology Imaging Findings: • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gout (Gouty Arthritis ... mass and NO prior signs ... relatively common, so ... • PVNS/Giant Cell ... diagnosis #msk #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• May involve PNS ... neuropathy • Transverse ... vein thrombosis Hematologic ... lymphopenia, low PLT • Anemia ... Chronic B-cell activation
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... peripheral neuropathy, transverse ... , INC risk PE, Pulmonary ... Nephrogenic DI Hematologic ... Arthralgia and Arthritis
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... systemic complaints- anemia ... identifies 85 to 95% of cases ... initiating steroids, so ... GCA #Temporal #Signs
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... May develop in pts ... tract, and often causes ... arthritis. ... Differential #Diagnosis #Rheumatology
Cutaneous Mucormycosis Eschar 30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
immunosuppressed pts ... cutaneous mucor cases ... hem CA, HSCT, SOT ... trauma, aplastic anemia ... Mucormycosis #Eschar #dermatology
Cryptococcal meningitis on T2 MRI 30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
MRI 30 M from sub-Saharan ... & results from reactivation ... of prior silent pulmonary ... organism (soap bubble sign ... Nausea & vomiting
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