11 results
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... • PCH • PNH ... immune-complex hemolytic anemia ... Diagnosis #Algorithm #Causes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... hemoglobinuria (PNH ... #Causes #differential ... #diagnosis #hematology ... #anemia
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
- Water - Pus ... Barre - ALS - Transverse ... myelitis • Hematology ... : - Anemia • ... Pain #dyspnea #sob
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
erythema, fever & lymphadenopathy ... erythema, fever & lymphadenopathy ... poor feeding, SOB ... & hemorrhagic rash ... CNS and hematologic
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
pain • Bulky lymphadenopathy ... -> AML: Blast crises ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
No evidence of anemia ... hyperviscosity, lymphadenopathy ... insufficiency, Anemia ... #Significance #hematology ... #diagnosis #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Exam/Signs: • Lymphadenopathy ... • Neutropenia, anemia ... Intussusception, SIB ... diagnosis #workup #oncology ... #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
and generalized lymphadenopathy ... nervous system (CNS ... Petechial or purpuric rash ... with leukopenia, anemia ... Diagnosis #Management #Hematology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
syndrome): - Hematologic ... (disseminated intravascular ... Treat underlying cause ... - CRS: fever, rash ... pulmonary opacities, SOB
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Presentation: • Lymphadenopathy ... Weight loss • Anemia ... Immune hemolytic anemia ... classification #hematology ... #oncology #management