11 results
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
- Asthma - COPD ... - Water - Pus ... Hepatopulmonary syndrome ... Barre - ALS - Transverse ... myelitis • Hematology
Genital Skin Ulcers - Differential Diagnosis Algorithm
Painful:
 • Herpes simplex
 • Haemophilus ducreyi (chancroid)
 • Behcet's
Differential Diagnosis Algorithm ... ) • Behcet's syndrome ... Ulcers #ulcerative #skinrash ... #dermatology #Differential ... #causes
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... deficiencies - PNH ... Associated - SLE, Sjogren's ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Recurrent / Breakthrough DVT During Anticoagulation

Subtherapeutic Anticoagulation
Hypercoagulable State 
 - Antithrombin deficiency 
 - Hypercoagulability ot
APLS - MPN/PNH ... Structural - Pelvic masses ... - May-Thurner syndrome ... anticoagulation #hematology ... #differential #algorithm
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... peripheral neuropathy, transverse ... Nephrogenic DI Hematologic ... #Syndrome #Rheumatology ... #Diagnosis #Management
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Muehrcke's Lines - Transverse ... • Nephrotic syndrome ... Systemic #Secondary #dermatology ... Differential #Diagnosis #Algorithm ... #causes
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... Rule out other causes ... inflammatory changes: CRP ... diagnosis #management ... #Dermatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
rate + Normal CRP ... dermatomyositis, Sjogren ... Malignancy (e.g. hematologic ... • May involve PNS ... neuropathy • Transverse
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... an underlying cause ... Better call hematology ... JAK2 V617F) and MPNs ... #workup #hematology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
erythematosus (SLE), Sjögren ... histopathologic changes in LNs ... levels - Increased CRP ... TAFRO #diagnosis #management ... #rheumatology #