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diagnosis rheumatology differential associations comparison connectivetissuediseases ctild dyspnea erythematosus ild lungdisease lupus nonpalpable palpable polychondritis prs purpura relapsing renal sapho
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Asthma - COPD ... - Water - Pus ... Hepatopulmonary syndrome ... Barre - ALS - Transverse ... myelitis • Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... deficiencies - PNH ... Associated - SLE, Sjogren's ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
OP: organizing pneumonia ... PSS: Sjogren syndrome ... Comparison #Table #Pulmonary ... #Rheumatology #
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... peripheral neuropathy, transverse ... Nephrogenic DI Hematologic ... #Syndrome #Rheumatology ... #Diagnosis #Management
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... Renal Syndromes ... EGPA • ESR and CRP ... Goodpasture's cause ... #diagnosis #management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... Rule out other causes ... inflammatory changes: CRP ... diagnosis #management ... #Dermatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
rate + Normal CRP ... dermatomyositis, Sjogren ... Malignancy (e.g. hematologic ... • May involve PNS ... neuropathy • Transverse
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Elevated ESR and CRP ... Mucocutaneous lymph node syndrome ... tract, and often causes ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
erythematosus (SLE), Sjögren ... histopathologic changes in LNs ... levels - Increased CRP ... TAFRO #diagnosis #management ... #rheumatology #
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
hearing loss, nausea ... Most common • Sjogren ... Nonspecific ↑ ESR, CRP ... Polychondritis #rheumatology ... #diagnosis #management
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