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differential algorithm management anemia hemolytic oncology workup table thrombocytopenia classification intravascular mcv pancytopenia reactions systemic treatment aflp arterial autoimmune blood
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... uremic syndrome ... hemoglobinuria (PNH ... #hematology #anemia
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... syndrome (ST-HUS ... anemia" • HELLP syndrome ... #differential #diagnosis ... #hematology #hemolysis
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... #Differential #Causes ... #Workup #Hematology ... #Diagnosis *
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential Diagnosis ... • PCH • PNH ... #Algorithm #Causes ... #Hematology
Causes of Hemolytic Anemia - Differential Diagnosis Inherited • Membrane • Internal - Hemoglobin
Causes of Hemolytic ... - Differential Diagnosis ... Sophia_Hayes_MD #Hemolytic ... #Differential #Diagnosis ... #Causes #hematology
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Cold Autoimmune Hemolytic ... Warm Autoimmune Hemolytic ... Cold Autoimmune Hemolytic ... #Anemia #hematology ... #diagnosis #comparison
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Differential Diagnosis ... - Water - Pus ... Hepatopulmonary syndrome ... Barre - ALS - Transverse ... myelitis • Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... DIC/TTP/HUS - Hemolytic ... deficiencies - PNH ... #hematology #rheumatology ... #nonpalpable #dermatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute hemolysis ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential Diagnosis ... iron deficiency, hemolysis ... Myelodysplastic syndrome ... #Causes #hematology
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