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diagnosis dermatology differential rheumatology systemic algorithm pruritus secondary basics erythematosus key leukemia lupus management nomenclature nonpalpable oncology palpable purpura pustular
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... Causes == Primary ... Skin Lesions == ... Skin Lesion / Systemic ... Myelodisplastic syndrome
Pustular Skin Lesions - Differential Diagnosis Framework What are pustules? • Pustules < 5-10 mm + pus • Material
Pustular Skin Lesions ... SAPHO syndrome ( ... Eosinophilic folliculitis ... Acute generalized ... Sweet syndrome
Primary Dermatological Lesions Primary lesions are physical changes in the skin considered to be caused directly by
Lesions Primary ... considered to be caused ... or part of a generalized ... #Skin #Primary ... #Nomenclature #Atlas
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... lesions that result ... /Quantity: • Primary ... Kasabach-Merritt syndrome ... deficiencies - PNH
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... Skin Lesion - Differential ... Myelodisplastic syndrome ... secondary #systemic #generalized ... Diagnosis #Algorithm #causes
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
with GCA or as primary ... Rash, arthritis Primary ... progressive) EGPA (Eosinophilic ... Polyangiitis): • Eosinophilia ... tract, and often causes
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... Vaginal dryness • Primary ... Hypocomplementemia • Can cause ... peripheral neuropathy, transverse ... Nephrogenic DI Hematologic
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
• (Peripheral eosinophilia ... + distinctive primary ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Leukemia #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... papulosquamous lesions ... the context of primary ... • May involve PNS ... neuropathy • Transverse
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