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diagnosis differential management cardiology infections infectiousdiseases treatment activetb endocarditis hepatology hivaids latenttb syndrome tb tuberculosis abscess aids allergy aspergillus betadglucan
Radiographic appearances of pulmonary diseases in HIV/AIDS Patients • Diffuse Interstitial Infiltrates: Pneumocystis jirovecii, M.tuberculosis, Histoplasma
diseases in HIV ... complex • Nodular/Masses ... ., NHL; Lung cancer ... • Pleural effusion ... tuberculosis Infectious
Pulmonary Infections in HIV-AIDS Bacterial: • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
Pulmonary Infections ... in HIV-AIDS Bacterial ... CD4 < 200: CMV, HSV ... failure, COPD, Lung ... Diseases Fellows
Causes of Pleural Effusion - Differential Diagnosis Algorithm Transudate - Hydrostatic • Congestive heart failure • Constrictive
Causes of Pleural ... Diagnosis Algorithm ... Pneumonectomy • Trapped lung ... Urinothorax Exudate - Infectious ... #Effusion #Pulmonary
Causes of Hypoxemia- Differential Diagnosis Algorithm Ventilation/perfusion Mismatch • Airway Disease (Asthma, COPD) • Vascular (PE*) •
Causes of Hypoxemia ... • Interstitial lung ... disease • Pulmonary ... Neuromascular Weakness • Pleural ... #Causes #Pulmonary
Causes of Dyspnea - Differential Diagnosis Algorithm Cardiac: • Dysrhythmia • Ischemia • Cardiomyopathy • Valvular disease
Causes of Dyspnea ... Differential Diagnosis Algorithm ... • Interstitial lung ... : • Pleural effusion ... #Causes
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
Causes of Pericardial ... Effusion - Differential ... Diagnosis Infectious ... Coxiella burnetii • Fungal ... - Metastatic: Lung
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
friction rub audible Lungs ... effusion on CXR ... inflammation tends to cause ... interstitial lung ... disease/pulmonary
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... Pseudomonas FUNGAL ... factor • May cause ... #Infections #HIV ... #AIDS #pulmonary
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
infection (IFI) ... surfaces - Infections ... colonization vs invasive disease ... Clav (may be + as long ... setting of GVHD) ID
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Active TB: • HIV ... (NTM) • Fungal ... • HIV: 2/3 pulmonary ... organ system: • Pleura ... : • HIV-infected
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