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differential oncology treatment algorithm hemophagocytic hlh leukemia lymphocytic lymphohistiocytosis vasculitis approach arthritis causes classification common comparison cvid diagnossi disease druginduced
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... : • Most common ... Lymphadenopathy • Fevers ... #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... Overview: • Most ... ) B symptoms → fevers ... Leukemia #oncology #hematology ... #management
Kawasaki Disease (KD) - Diagnosis and Management Summary Kawasaki Disease (KD) is the most common vasculitis of
Disease (KD) is the most ... Presentation: • Fever ... Criteria - Fever ... KD #vasculitis #rheumatology ... #pediatrics #diagnossi
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... lymphoma, B-cell ... chemotherapy, anti-CD20 (PTLD ... #management #treatment ... #summary #rheumatology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Better call hematology ... normal/high - Chronic ... you’ll do a good workup ... #Algorithm #workup ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
presentation, and most ... following: • Fever ... Low or absent NK cell ... #management #treatment ... #hematology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
to Joint Pain - Diagnostic ... acute rheumatic fever ... • Chronic - Think ... Joint #Pain #MSK #rheumatology ... #approach #workup
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Epidemiology: -10% of all ... • Immunologic Workup ... • Evolution: Chronic ... comparison #table #rheumatology ... #diagnosis #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... Autoimmunity • Chronic ... other cancers: Most ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Causes of Fever ... Immunocompromised Host ... - Differential Diagnosis ... Bronchitis • Chronic ... Algorithm #Causes #Hematology
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