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differential oncology lymphoma management agglutinin aplastic causes classification comparison disease disorders gap globulin hemolytic nonhodgkins platelet protein proteingap thrombocytopenia
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Immunosuppression (e.g., HIV), EBV ... Extranodal disease: GI, neuro ... Differential Diagnosis ... • Other hematologic ... #differential #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... Weight loss • Anemia ... Immune hemolytic anemia ... Workup: • Full ... classification #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... anemia • Cold ... - Mycoplasma, EBV ... sensitize red blood cells ... #hematology #diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Toxic injury to BM ... Anticonvulsants - Gold ... Parvovirus B19 - EBV ... #oncology #hematology ... #diagnosis #management
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... practices that could ... changes), high MCV anemia ... When do you do a BM
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... acute HIV, HBV, EBV ... Thalassemia, Sickle cell anemia ... #differential #diagnosis ... #hematology
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