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diagnosis oncology differential management agglutinin algorithm aplastic classification cold disease gap globulin hemolytic hepatitis hepatology hodgkins injury leukemia liver lymphoma
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Toxic injury to BM ... and petechiae Causes ... Parvovirus B19 - EBV ... Epstein-Barr virus (EBV ... #oncology #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... • hemolytic anemia ... - Mycoplasma, EBV ... sensitize red blood cells ... #hematology #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... HBV, HCV, HEV, EBV ... , PSC, IgG4, HLH ... intestines, white blood cells ... diagnosis #algorithm #hepatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... • History of EBV ... Weight loss • Anemia ... Immune hemolytic anemia ... classification #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
- Blood & BM • ... • Cytopenia -> BM ... -> AML: Blast crises ... - infiltrates (anemia ... #Leukemia #Hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Causes of Monoclonal ... acute HIV, HBV, EBV ... gastric tumors • Hematology ... Thalassemia, Sickle cell anemia ... differential #diagnosis #hematology
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