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diagnosis algorithm hematology hepatology liver rheumatology acute agglutinin causes cold erythematosus gap globulin hemolytic hepatitis lupus myopathy myositis protein proteingap
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... C, A, E, B, D, EBV ... Other: NAFLD, Autoimmune ... , 1° PSC, Cystic ... #Injury #Differential
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Injury: • Infectious ... HBV, HCV, HEV, EBV ... • Autoimmune: ... Autoimmune hepatitis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Donath-Landsteiner Antibodies[PCH ... , autoimmune disorder ... - Mycoplasma, EBV ... pts) Differential ... Hemoglobinuria (PCH
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Include: • Viral infections ... acute HIV, HBV, EBV ... , ETOH, autoimmune ... Thalassemia, Sickle cell anemia ... Gap #ProteinGap #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... fibromyalgia) • Infections ... pericardial/abd GI ... Antiribosomal P, APLA, PAC ... lymphopenia, low PLT • Anemia
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... Tenderness → Consider infectious ... • ANA < 20 % IBM ... : • PBC, autoimmune ... #rheumatology #differential
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