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diagnosis oncology algorithm hepatology hodgkins injury rheumatology acute agglutinin aids autoimmune causes classification cold comparison disease erythematosus gap globulin hemolytic
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute Liver ... Hepatocellular - Liver ... C, A, E, B, D, EBV ... Artery: Shock Liver ... Sophia_Hayes_MD #Liver
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... HBV, HCV, HEV, EBV ... cell lung CA, lymphoma ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Immunosuppression (e.g., HIV), EBV ... the spleen or liver ... lymphadenopathy, mass ... • Other hematologic ... #hematology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... lesions < 4cm + mass ... diameter - +mass ... effect/Edema • EBV ... #Infections #differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
- Monoclonal - Lymphoid ... - Mycoplasma, EBV ... younger pts) Differential ... Hemoglobinuria (PCH ... #hematology #diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... Weight loss • Anemia ... Immune hemolytic anemia ... Immunohistochemical studies (to differentiate ... classification #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Amyloidosis • Lymphoma ... acute HIV, HBV, EBV ... Sarcoidosis) • Liver ... Thalassemia, Sickle cell anemia ... Gap #ProteinGap #differential
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL: mediastinal mass ... cells - Blood & BM ... • Cytopenia -> BM ... - infiltrates (anemia ... #Leukemia #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Angioimmunoblastic T-cell lymphoma ... and CNS • Headache ... Antiribosomal P, APLA, PAC ... lymphopenia, low PLT • Anemia
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... stomach, colon, and lymphoma ... • ANA < 20 % IBM ... Other Diseases: • PBC ... #differential #
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