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Hypoxia and Hypoxemia - Overview Hypoxia - insufficient oxygen delivered to tissues to meet demands Hypoxemia - low
O2 is inspired) PAO2 ... hypoxia) - Low PaO2 ... Low SvO2 → Low PaO2 ... Low SvO2 → Low PaO2 ... summary #pulmonary #differential
Approach to the A-a Gradient A-a gradient = PAO2 - PaO2 A-a gradient = [FiO2 x (Patm -
A-a gradient = PAO2 ... - PaO2 A-a gradient ... /0.8)] - PaO2 Simplified ... /0.8)] - PaO2 Normal ... Hypoxia #hypoxemia #differential
Acid-Base Disorders - Differential Diagnosis Algorithm Acidemia (pH < 7.35) • Metabolic Acidosis (HCO3 < 24mmol/L) CO2
Acid-Base Disorders - Differential ... Respiratory Acidosis (pCO2 ... Respiratory Alkalosis (pCO2 ... < 35 mmHg) #AcidBase ... #Disorders #Differential
Arterial Blood Gas (ABG) Analysis - Metabolic + Respiratory Acidosis + Alkalosis pH ↓ pCO2 ↓ -
Alkalosis pH ↓ pCO2 ... acidosis pH ↑ pCO2 ... alkalosis pH ↑ pCO2 ... alkalosis pH ↓ pCO2 ... Interpretation #AcidBase
Acid Base Compensation - Directions - If all three variables (pH, HCO2, pCO2) move in the
variables (pH, HCO2, pCO2 ... Diagnosis #Nephro #AcidBase
PLACO Mnemonic - Approach to Acid-Base Disorders P - Determine the pH L - Labs: PCO2 & HCO3 A
pH L - Labs: PCO2 ... jadav_md #PLACO #AcidBase
Acid-Base Disorders - Differential Diagnosis Framework • Respiratory Acidosis • Respiratory Alkalosis • Metabolic Acidosis •
Acid-Base Disorders - Differential ... Kfischer_10 #AcidBase ... Disorders #nephrology #differential
Acid Base Disorders - Blood Gas Interpretation Steps for Blood Gas Interpretation: 1. Acidemia or Alkalemia? 2.
Differentials? ... 35-45 mmHg • PaO2 ... acidosis Step 5 - Differential ... MDaniyalHashmi1 #AcidBase ... Base #Gas #VBG #differential
Acid Base and Blood Gas Analysis 1. pH - What’s the primary disturbance? 2. pCO2 - What’s the
2. pCO2 - What’s ... the pCO2? ... MD @nickmmark #acidbase
Hypoxemia vs Hypoxia Hypoxemia - Partial pressure of arterial oxygen (PaO2) is below normal Hypoxia - Insufficient oxygen
arterial oxygen (PaO2 ... compensate for low PaO2 ... hypoxia #hypoxemia #differential
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