8 results
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
- Pharmacology ... Risk of reflex bradycardia ... • Higher doses cause ... cAMP/cGMP • Causes ... #Pharmacology #
Cardiac Stress Testing
Exercise:
 • Everyone who can exercise should!
 • They must be able to raise
production to cause ... Contraindications: - Bradycardia ... heartblock w/o pacemaker ... and asthma • Inotropes
Common Medications Known to Prolong QTc
Antiarrhythmics - Amiodarone, sotalol, flecainide, quinidine, dronedarone, dofetilide
Vasopressors/inotropes - Epinephrine, norepinephrine,
to Prolong QTc Antiarrhythmics ... Vasopressors/inotropes ... #Medications #Causes ... differential #diagnosis #pharmacology
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
Vasopressors and Inotropes ... effects: Reflex bradycardia ... Bradyarrhythmias, Some cases ... #Vasopressors #Inotropes ... comparison #table #pharmacology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Antiarrhythmics ... force (negative inotropy ... accpcardprn #Antiarrhythmics ... Vaughan #Williams #Pharmacology ... Classification #Classes
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics ... Pharmacology Summary ... force (negative inotropy ... #Pharmacology # ... Classification #Classes
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
hypotension and bradycardia ... hypotension, and bradycardia ... vera, Licorice - Causes ... arrhythmias Class I Antiarrhythmic ... supplementals #herbal #pharmacology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
patients need inotrope ... the determined cause ... #differential #algorithm ... icu #clinical #pharmacology