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Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
Inotropes - Pharmacology ... Risk of reflex bradycardia ... • Higher doses cause ... cAMP/cGMP • Causes ... #Inotropes #Pharmacology
Vasopressors and Inotropes
 • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
Vasopressors and ... Inotropes • Norepinephrine ... ), Symptomatic bradycardia ... #Inotropes #management ... comparison #table #pharmacology
Vasopressors Table 
Rough properties by Target Receptor, Heart Rate/Inotropy, Systemic Vascular Resistance, Cardiac Output, Blood Pressure,
Vasopressors Table ... Receptor, Heart Rate/Inotropy ... Resistance, Main Uses ... Properties #Table #Pharmacology ... Management #Comparison #Inotropes
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
Common Vasopressors ... and Inotropes Norepinephrine ... effects: Reflex bradycardia ... #Inotropes #comparison ... #table #pharmacology
Cardiac Stress Testing
Exercise:
 • Everyone who can exercise should!
 • They must be able to raise
production to cause ... Contraindications: - Bradycardia ... heartblock w/o pacemaker ... and asthma • Inotropes
Common Medications Known to Prolong QTc
Antiarrhythmics - Amiodarone, sotalol, flecainide, quinidine, dronedarone, dofetilide
Vasopressors/inotropes - Epinephrine, norepinephrine,
dronedarone, dofetilide Vasopressors ... /inotropes - Epinephrine ... #Medications #Causes ... differential #diagnosis #pharmacology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
patients need inotrope ... the determined cause ... #differential #algorithm ... icu #clinical #pharmacology