11 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
• +ANA can be seen ... context of other symptoms ... likely it will be clinically ... , Sjögren Syndrome ... #patterns #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Syndrome Diagnosis ... ab • RF • Antinuclear ... #Syndrome #Rheumatology ... #Diagnosis #Management
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... Treatment of GCA ... them, but urgent rheumatology ... #Signs #Symptoms ... #Diagnosis #Management
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
knees, shoulders Signs ... & Symptoms: • ... : CLINICAL DIAGNOSIS ... #diagnosis #management ... #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
, AS Treatment: ... Nonsurgical abdominal pain ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... arterial aneurysms can ... Presentation - Systemic Symptoms ... purpura: strong sign ... #rheumatology #
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... CRP GCA (Giant ... develop in pts with GCA ... tract: Abdominal pain ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
syndrome associated ... : HLH signs and ... symptoms can mimic ... #management #treatment ... #hematology
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
Sudden onset of pain ... Most common • Sjogren ... , ANA + • Biopsy ... Polychondritis #rheumatology ... #diagnosis #management
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
IGG4 - Hepatic cirrhosis ... cell lymphoma Pathophysiology ... the systemic symptoms ... Hypoalbuminemia Treatment ... #management #rheumatology