8 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
• +ANA can be seen ... context of other symptoms ... likely it will be clinically ... , Sjögren Syndrome ... #rheumatology #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
syndrome associated ... : HLH signs and ... symptoms can mimic ... #diagnosis #management ... #treatment #hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Syndrome Diagnosis ... salivary ducts Clinical ... #Syndrome #Rheumatology ... #Diagnosis #Management
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... Treatment of GCA ... them, but urgent rheumatology ... #Signs #Symptoms ... #Diagnosis #Management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
to exclude are infections ... purpura: strong sign ... ) pattern: antibodies ... #rheumatology # ... classification
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... dermatomyositis, Sjogren ... fibromyalgia) • Infections ... Joint pain • Swan ... #Rheumatology
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
Sudden onset of pain ... Most common • Sjogren ... Polyarteritis Nodosa, GCA ... Polychondritis #rheumatology ... #diagnosis #management
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
symptomsRheumatologic ... , neutropenia, cirrhosis ... Aspergillosis Pathophysiology ... Meningitis, septic arthritis ... #Management #Infections