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dermatomyositis management antimda5 antimda5dm antinxp2dm common cvid hematology hypogammaglobulinemia immunodeficiency immunology variable
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... • Chronic lung ... lymphocytic interstitial lung ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
auricular papules Clinical ... anti-NXP2 Abs Lung ... Men • ~50% of cases ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
auricular papules Clinical ... Muscle atrophy may cause ... Non-small-cell lung ... #rheumatology # ... dermatology
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