9 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... , Palpable purpura ... • Palpable purpura ... • EGPAHenoch-Schönlein ... purpura • Mixed
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash - Differential ... Schonlein Purpura ... Rash: - Purpura ... #Petechiae #Rash
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Petechiae/Purpura ... Pathophysiology: ... #Petechiae #Purpura ... #Palpable #Algorithm ... #Differential #
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Small Vessel: Petechiae ... , Palpable purpura ... Urticarial/LCV) - Cryoglobulinemic ... - Microscopic polyangiitis ... - EGPA - GPA
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Purpura Anti-GBM ... #differential # ... diagnosis #algorithm
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Arthralgia - Purpura ... purpura, Arthralgia ... - GPA, EGPA, microscopic ... polyangiitis ... purpura) • Cutaneous
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: • Purpura, ischemic ... Schonlein Purpura ... erythematous nodules, purpura ... purpura: strong ... purpura.
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... : • Purpura, ischemic ... purpura: Strong ... purpura, joint ... ) • Palpable purpura
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
poor nutrition Clinical ... • Purpura • Perifollicular ... • Petechiae, purpura ... , or any other cause ... purpura • DIC