11 results
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
Petechial/Purpuric ... endocarditis, RMSF, and Henoch-Schönlein ... rash, the diagnosis ... #Diagnosis #Dermatology ... #Purpuric #Rash
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... PURPURA: Platelet ... OF PALPABLE PURPURA ... Diagnosis #hematology ... #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
purpura (16%) ... overlying purpuric ... polyangiitis • EGPA • Henoch-Schönlein ... purpura • Mixed ... #rash #diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Diagnosis Algorithm ... Schonlein Purpura ... Rash: - Purpura ... Diagnosis #Algorithm ... #Causes #dermatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Crohn's disease Palpable ... purpura • Hypersensitivity ... vasculitis • Henoch ... Schönlein purpura ... #diagnosis #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... IgA nephropathy, Henoch-SchonIein ... Purpura Anti-GBM ... #diagnosis #algorithm ... #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Arthralgia - Purpura ... purpura, Arthralgia ... IgA vasculitis (Henoch-Schönlein ... purpura) • Cutaneous ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitis: • Purpura ... Schonlein Purpura ... purpura: strong ... purpura. ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis: • Purpura ... purpura: Strong ... Schonlein Purpura ... purpura, joint ... #Diagnosis #Rheumatology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
to accumulated inflammatory ... rash, pruritis, ... Post Transfusion Purpura ... Causes purpura & ... #management #hematology