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diagnosis hematology blood product common cvid disease igg4 immunodeficiency immunology phenotypes related rheumatology transfusion transfusions treatment variable workup
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung ... • Liver diseases ... Chest CT: • Ground-glass ... and M panel Management ... DDX - Other causes
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... biliary, renal, lung ... concentration PET-CT ... • Polyclonal hypergammaglobulinemia ... #diagnosis #management
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... Related Acute Lung ... TRALI): Leading cause ... eruptions, diarrhea, liver ... Transfusion #diagnosis #management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Causes purpura & ... Related Acute Lung ... TRALI): Leading cause ... eruptions, diarrhea, liver ... Transfusions #diagnosis #management
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