10 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... head and neck, pancreas ... biliary, renal, lung ... concentration PET-CT ... #rheumatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung ... lymphocytic interstitial lung ... Chest CT: • Ground-glass ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
in literature (NEJM ... (Cornelia NEJM ... of the steroid treatment ... Treatment of GCA ... them, but urgent rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... MALT Lymphoma • Lung ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Mediastinal mass) • CT ... number of sites of disease ... physical exam, CT ... Hodgkin Lymphoma Treatment ... classification #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... Related Acute Lung ... TRALI): Leading cause ... TRALI resembles ARDS ... diagnosis #management #hematology
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary

WHAT?
 • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
of unknown cause ... subacromial-subdeltoid bursitis and long ... TREATMENT: • The ... mainstay of treatment ... Diagnosis #Management #Rheumatology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Causes purpura & ... Related Acute Lung ... TRALI): Leading cause ... TRALI resembles ARDS ... diagnosis #management #hematology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... , pancreas, stomach ... , pancreas, stomach ... statins - probably caused ... Myositis #Myopathy #rheumatology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
Muscle atrophy may cause ... had more severe disease ... Non-small-cell lung ... positive patients Treatment ... diagnosis #management #rheumatology