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diagnosis management differential liver algorithm gastroenterology pulmonary aclf amiodarone cardiology cirrhosis common cvid dili druginduced endocarditis failure hematology hepatitis hypogammaglobulinemia
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... underlying liver disease ... Brain Failure Lung ... Drug-Induced Liver Injury
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation causes ... bronchial wall injury ... Most Common Causes ... high-resolution chest CT ... mycobacteria Treatment
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Algorithm Vascular Causes ... CA, small cell lung ... > 3 • Chronic ... diagnosis #algorithm #hepatology
Chronic Pancreatitis Definition: A pathologic fibroinflammatory syndrome of the pancreas in individuals with genetic, environmental, and/or other
Chronic Pancreatitis ... syndrome of the pancreas ... to parenchymal injury ... • 1st line: CT ... gastroenterology #treatment
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... for alternative causes ... Alcohol-related liver disease ... dechallenge • Acute ... Diagnosis #Algorithm #hepatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Autoimmunity • Chronic ... lung disease ... • Bronchiectasis ... Chest CT: • Ground-glass ... DDX - Other causes
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
injury • Indirect ... • Chronic toxicity ... (e.g., chronic ... opacities; traction bronchiectasis ... Exclude other causes
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
, verrucous) - Lung ... , Pancreas, Gastric ... Culture Positive: • Acute ... injury by: • Early ... hematuria, + RF Treatment
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