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diagnosis management differential cardiology pulmonary hematology liver oncology syndromes aclf acute algorithm amiodarone anthracycline blood bronchiectasis cardiotoxicity chemotherapy cirrhosis complexes
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... underlying liver disease ... Lung Failure ... Liver Injury (DILI ... #Cirrhosis #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... non-essential drug/HDS treatments ... for alternative causes ... Alcohol-related liver disease ... Diagnosis #Algorithm #hepatology
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
Lung Toxicity Summary ... injury • Indirect ... • Chronic toxicity ... Exclude other causes ... #Lung #Toxicity
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
bronchial wall injury ... Most Common Causes ... in the adjacent lung ... high-resolution chest CT ... mycobacteria Treatment
Portopulmonary Hypertension Presence of pulmonary arterial hypertension in a patient with portal hypertension No other obvious causes (chronic
other obvious causes ... (chronic lung disease ... , left heart disease ... pressure < 15mmHg TREATMENT ... diagnosis #management #hepatology
Premature Ventricular Complexes (PVC's) - Summary Framework Why PVCs? Can be the first manifestation of cardiac
Causes: • Hypertension ... Substances • Digoxin toxicity ... Cardiomyopathy (PVC-induced ... beats) • Heart failure ... more intensive treatment
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
(DAH) & renal failure ... quantify renal injury ... Other tests: • CT ... sparing of the lung ... diagnosis #management #treatment
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
, verrucous) - Lung ... , Pancreas, Gastric ... New-onset heart failure ... injury by: • Early ... hematuria, + RF Treatment
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
hypoTN, renal failure ... Causes purpura & ... Related Acute Lung ... Injury (TRALI): ... Leading cause of
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Bone Marrow Failure ... • Chronic Myelogenous ... Myeloproliferative Disease ... unclassifiable: Reduced ... Syndromes #diagnosis #hematology
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