8 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... biliary, renal, lung ... concentration PET-CT ... #diagnosis #management ... workup #treatment #rheumatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung ... lymphocytic interstitial lung ... Chest CT: • Ground-glass ... and M panel Management ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
highly inflammatory disease ... rash) • Heart, lung ... Fibrin degradation products ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Related Acute Lung ... Graft Versus Host Disease ... Borrellia (Lyme disease ... Transfusions #diagnosis #management ... #hematology #reactions
Scleroderma Like Conditions - Differential Diagnosis
Eosinophilic Fasciitis:
 - Orange peel induration (peau d'orange) of proximal extremities
patients with kidney disease ... Typically seen in long-standing ... neck, and arms, deposition ... Exposure: - Can produce ... Differential #Diagnosis #comparison
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Related Acute Lung ... Blood products contain ... of transfused products ... Transfusion #diagnosis #management ... #hematology #reactions
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pyrophosphate Deposition ... Pyrophosphate produced ... ≥2 attacks • Long-term ... #Disease #Rheumatology ... #diagnosis #management
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
pulmonary symptoms • Rheumatologic ... dissemination occurs and produces ... change in the lungs ... nails, bronchi, lungs ... Fungal #Diagnosis #Management