8 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
Clinical history ... biliary, renal, lung ... concentration PET-CT ... increased IgG4+ cells ... 40% supporting long-term
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... (GCA) Giant cell ... Diagnosis = clinical ... in literature (NEJM ... cases (Cornelia NEJM
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome Diagnosis ... ducts Clinical ... Arthralgia and Arthritis ... MALT Lymphoma • Lung ... Adenocarcinoma Treatment
Squamous-Cell Carcinoma of the Lung- ...Physical examination revealed decreased air entry in the base of the
Squamous-Cell Carcinoma ... biopsy confirmed a diagnosis ... indicated stage IV disease ... #NEJM #clinical ... #radiology #CT #
Pyoderma Gangrenosum in Ulcerative Colitis- ...left chest (Panel A) and leg (Panel B). The physical examination
mixed inflammatory-cell ... A diagnosis of pyoderma ... #clinical #photo ... #NEJM #pyoderma ... ulcerative #colitis #derm
Thumbprinting in Ischemic Colitis- Contrast-enhanced computed tomography of the abdomen, performed to evaluate the possibility of
infectious colitis, as well ... consistent with a diagnosis ... ischemic #colitis #clinical ... #radiology #CT ... thumbprinting #sign #NEJM
Lichen Planus- ...On examination, numerous purple papules were noted on the anterior surface of the forearms
confirming the diagnosis ... an autoimmune disease ... used in primary treatment ... #NEJM #clinical ... lichen #planus #derm
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
has five major clinical ... change in the lungs ... becomes a yeast cell ... Meningitis, septic arthritis ... nails, bronchi, lungs