8 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... Clinical history ... concentration PET-CT ... 40% supporting long-term ... #rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... in literature (NEJM ... cases (Cornelia NEJM ... Treatment of GCA ... them, but urgent rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Fever is the main clinical ... rash) • Heart, lung ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
culture used to diagnose ... Acute Pseudogout: Treatment ... ≥2 attacks • Long-term ... #Rheumatology # ... diagnosis #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
salivary ducts Clinical ... Arthralgia and Arthritis ... MALT Lymphoma • Lung ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Squamous-Cell Carcinoma of the Lung- ...Physical examination revealed decreased air entry in the base of the
Carcinoma of the Lung ... biopsy confirmed a diagnosis ... indicated stage IV disease ... #NEJM #clinical ... #radiology #CT #
Lichen Planus- ...On examination, numerous purple papules were noted on the anterior surface of the forearms
confirming the diagnosis ... an autoimmune disease ... used in primary treatment ... #NEJM #clinical ... lichen #planus #derm
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
pulmonary symptoms • Rheumatologic ... has five major clinical ... change in the lungs ... Meningitis, septic arthritis ... nails, bronchi, lungs