9 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
Clinical history ... biliary, renal, lung ... concentration PET-CT ... increased IgG4+ cells ... #diagnosis #management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
macrophages and T cells ... Langerhans giant cells ... characteristic features Clinical ... Tuberculosis Diagnosis ... #Management #Treatment
Thumbprinting in Ischemic Colitis- Contrast-enhanced computed tomography of the abdomen, performed to evaluate the possibility of
, as well as in ... consistent with a diagnosis ... #clinical #radiology ... #CT #thumbprinting ... #sign #NEJM
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
macrophages and T cells ... Langerhans giant cells ... characteristic features Clinical ... Tuberculosis Diagnosis ... #Management #Treatment
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... to 8 years Clinical ... • Chronic lung ... Chest CT: • Ground-glass ... #management
Disseminated Actinomycosis- ...Computed tomography of the chest and abdomen revealed multiple pulmonary nodules (Panel A) associated
effusions in both lungs ... Biopsy of the lung ... patient received a diagnosis ... #NEJM #clinical ... #radiology #CT #
Squamous-Cell Carcinoma of the Lung- ...Physical examination revealed decreased air entry in the base of the
Squamous-Cell Carcinoma ... biopsy confirmed a diagnosis ... indicated stage IV disease ... #NEJM #clinical ... #radiology #CT #
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... Diagnosis = clinical ... in literature (NEJM ... cases (Cornelia NEJM ... #Management
Pyoderma Gangrenosum in Ulcerative Colitis- ...left chest (Panel A) and leg (Panel B). The physical examination
mixed inflammatory-cell ... A diagnosis of pyoderma ... inflammatory bowel disease ... #clinical #photo ... #NEJM #pyoderma