8 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... biliary, renal, lung ... concentration PET-CT ... increased IgG4+ cells ... #diagnosis #management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... • Chronic lung ... Chest CT: • Ground-glass ... and M panel Management ... #management
Disseminated Actinomycosis- ...Computed tomography of the chest and abdomen revealed multiple pulmonary nodules (Panel A) associated
effusions in both lungs ... Biopsy of the lung ... patient received a diagnosis ... #NEJM #clinical ... #radiology #CT #
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... (GCA) Giant cell ... in literature (NEJM ... cases (Cornelia NEJM ... #Management
Squamous-Cell Carcinoma of the Lung- ...Physical examination revealed decreased air entry in the base of the
Squamous-Cell Carcinoma ... biopsy confirmed a diagnosis ... indicated stage IV disease ... #NEJM #clinical ... #radiology #CT #
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
verrucous) • Lung ... , Pancreas, Gastric ... Differential Diagnosis ... Regurgitation • Colon ... #management #cardiology
Thumbprinting in Ischemic Colitis- Contrast-enhanced computed tomography of the abdomen, performed to evaluate the possibility of
of the sigmoid colon ... consistent with a diagnosis ... colitis #clinical #radiology ... #CT #thumbprinting ... #sign #NEJM
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
had more severe disease ... carcinoma • Clear cell ... lung carcinoma ... macroglobulinemia Lung ... #diagnosis #management