15 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... biliary, renal, lung ... concentration PET-CT ... increased IgG4+ cells ... #diagnosis #management
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... and Management ... infection • Most common ... seen • Chest CT ... Management: •
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... • Chronic lung ... lymphocytic interstitial lung ... Chest CT: • Ground-glass ... #management
Disseminated Actinomycosis- ...Computed tomography of the chest and abdomen revealed multiple pulmonary nodules (Panel A) associated
effusions in both lungs ... Biopsy of the lung ... patient received a diagnosis ... #NEJM #clinical ... #radiology #CT #
Thumbprinting in Ischemic Colitis- Contrast-enhanced computed tomography of the abdomen, performed to evaluate the possibility of
of the sigmoid colon ... , as well as in ... consistent with a diagnosis ... clinical #radiology #CT ... thumbprinting #sign #NEJM
Squamous-Cell Carcinoma of the Lung- ...Physical examination revealed decreased air entry in the base of the
Squamous-Cell Carcinoma ... biopsy confirmed a diagnosis ... indicated stage IV disease ... #NEJM #clinical ... #radiology #CT #
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... in literature (NEJM ... cases (Cornelia NEJM ... day, followed by long ... #Management
Pyoderma Gangrenosum in Ulcerative Colitis- ...left chest (Panel A) and leg (Panel B). The physical examination
mixed inflammatory-cell ... A diagnosis of pyoderma ... the second most common ... inflammatory bowel disease ... clinical #photo #NEJM
Ear Pain (Otalgia) - Differential Diagnosis Framework

Primary Otalgia 
 - Pain that originates from the ear
- Differential Diagnosis ... otalgia Most Common ... Basal/squamous cell ... otalgia Most Common ... subdural hematoma, lung
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
verrucous) • Lung ... , Pancreas, Gastric ... Differential Diagnosis ... Regurgitation • Colon ... #management #cardiology