9 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... biliary, renal, lung ... concentration PET-CT ... increased IgG4+ cells ... #diagnosis #management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... • Chronic lung ... lymphocytic interstitial lung ... Chest CT: • Ground-glass ... #management
Disseminated Actinomycosis- ...Computed tomography of the chest and abdomen revealed multiple pulmonary nodules (Panel A) associated
effusions in both lungs ... Biopsy of the lung ... patient received a diagnosis ... #NEJM #clinical ... #radiology #CT #
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
- Differential Diagnosis ... Framework Disease ... • CT: Halo sign ... • Risk: Can produce ... Infections #HIV #AIDS
Squamous-Cell Carcinoma of the Lung- ...Physical examination revealed decreased air entry in the base of the
Squamous-Cell Carcinoma ... biopsy confirmed a diagnosis ... indicated stage IV disease ... #NEJM #clinical ... #radiology #CT #
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Related Acute Lung ... TRALI resembles ARDS ... potassium from lysed cells ... #Transfusions #diagnosis ... #management #hematology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... in literature (NEJM ... cases (Cornelia NEJM ... day, followed by long ... #Management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Related Acute Lung ... TRALI resembles ARDS ... potassium from lysed cells ... #Transfusion #diagnosis ... #management #hematology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
droppings • Most common ... dissemination occurs and produces ... yeast • At risk: AIDS ... change in the lungs ... #Management #Infections