10 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
Clinical history ... biliary, renal, lung ... concentration PET-CT ... increased IgG4+ cells ... #diagnosis #management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... to 8 years Clinical ... Chest CT: • Ground-glass ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Disseminated Actinomycosis- ...Computed tomography of the chest and abdomen revealed multiple pulmonary nodules (Panel A) associated
effusions in both lungs ... Biopsy of the lung ... patient received a diagnosis ... #NEJM #clinical ... #radiology #CT #
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Advanced HIV (CD4 cell ... Hematologic malignancy ... Lung Disease: ... • Clinical (Symptoms ... Imaging, high res CT
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... Diagnosis = clinical ... in literature (NEJM ... cases (Cornelia NEJM ... #Management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome Diagnosis ... ducts Clinical ... Nephrogenic DI Hematologic ... MALT Lymphoma • Lung ... #Diagnosis #Management
Squamous-Cell Carcinoma of the Lung- ...Physical examination revealed decreased air entry in the base of the
Squamous-Cell Carcinoma ... biopsy confirmed a diagnosis ... indicated stage IV disease ... #NEJM #clinical ... #radiology #CT #
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... number of sites of disease ... physical exam, CT ... classification #hematology ... #oncology #management
Thumbprinting in Ischemic Colitis- Contrast-enhanced computed tomography of the abdomen, performed to evaluate the possibility of
infectious colitis, as well ... consistent with a diagnosis ... ischemic #colitis #clinical ... #radiology #CT ... thumbprinting #sign #NEJM
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
auricular papules Clinical ... had more severe disease ... carcinoma • Clear cell ... lung carcinoma ... #management #rheumatology