12 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
Clinical history ... biliary, renal, lung ... concentration PET-CT ... increased IgG4+ cells ... #diagnosis #management
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Somatic) Syndrome Clinical ... Syndrome: • Common Clinical ... thromboembolic disease ... NEJM Review: https ... Autoinflammatory #Somatic #rheumatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... to 8 years Clinical ... • Chronic lung ... Chest CT: • Ground-glass ... #diagnosis #management
Echinococcal Cysts in the Liver- The physical examination revealed hepatomegaly with a palpable hepatic mass. Laboratory
a normal white-cell ... Hydatid disease ... #clinical #NEJM ... hepatic #radiology #CT
Disseminated Actinomycosis- ...Computed tomography of the chest and abdomen revealed multiple pulmonary nodules (Panel A) associated
effusions in both lungs ... Biopsy of the lung ... infection caused by actinomyces ... #NEJM #clinical ... #radiology #CT #
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... in literature (NEJM ... cases (Cornelia NEJM ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Squamous-Cell Carcinoma of the Lung- ...Physical examination revealed decreased air entry in the base of the
Squamous-Cell Carcinoma ... indicated stage IV disease ... #NEJM #clinical ... #radiology #CT # ... squamous #cell #
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
multisystemic disease ... ducts Clinical ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Mediastinal mass) • CT ... number of sites of disease ... physical exam, CT ... #oncology #management
Thumbprinting in Ischemic Colitis- Contrast-enhanced computed tomography of the abdomen, performed to evaluate the possibility of
complicated diverticular disease ... infectious colitis, as well ... ischemic #colitis #clinical ... #radiology #CT ... thumbprinting #sign #NEJM