10 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... Clinical history ... concentration PET-CT ... #diagnosis #management ... workup #treatment #rheumatology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Somatic) Syndrome Clinical ... Syndrome: • Common Clinical ... thromboembolic disease ... myeloid cells NEJM ... Autoinflammatory #Somatic #rheumatology
Disseminated Actinomycosis- ...Computed tomography of the chest and abdomen revealed multiple pulmonary nodules (Panel A) associated
Disseminated Actinomycosis ... effusions in both lungs ... Biopsy of the lung ... #NEJM #clinical ... #radiology #CT #
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... • Chronic lung ... Chest CT: • Ground-glass ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... rash) • Heart, lung ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... in literature (NEJM ... cases (Cornelia NEJM ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... number of sites of disease ... physical exam, CT ... classification #hematology ... #oncology #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
salivary ducts Clinical ... Nephrogenic DI Hematologic ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Squamous-Cell Carcinoma of the Lung- ...Physical examination revealed decreased air entry in the base of the
Carcinoma of the Lung ... base of the right lung ... indicated stage IV disease ... #NEJM #clinical ... #radiology #CT #
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
auricular papules Clinical ... had more severe disease ... Non-small-cell lung ... Dermatomyositis #diagnosis #management ... #rheumatology #