10 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... Clinical history ... concentration PET-CT ... 40% supporting long-term ... IgG4 #Related #Disease
Plain radiography of the abdomen revealed calcification of both adrenal glands. A homozygous mutation in LIPA
confirmed the diagnosis ... deficiency, or Wolman’s disease ... #clincial #peds ... #infant #NEJM # ... Wolmans #radiology #xray
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
and Clinical Features ... ) Peptic Ulcer disease ... rarely in Cushing's disease ... 2) Cushing's disease ... • In Cushing's disease
Miliary Pattern - Chest Radiology
 • Miliary opacities are scattered, small (1 -4 mm) nodules
 •
throughout the lungs ... hematogenous spread of a disease ... thyroid, melanoma, renal ... pulmonary #CXR #clinical ... #CT
Clinical Manifestations of Sickle Cell Disease

Anaemia
Infection
Painful crises
Priapism
Splenomegaly
Long Term Problems - Short stature and delayed puberty, Stroke
Clinical Manifestations ... of Sickle Cell Disease ... Term Problems - ... #SickleCell #Disease ... Signs #Symptoms #Diagnosis
Broncholithiasis - Differential Diagnosis Framework

 • Also known as: Lung stones, pulmoliths, pneumoliths, bronchial calculi
 •
Also known as: Lung ... Broncholithiasis - Clinical ... : • Chest Xray ... bronchus • Chest CT ... Tracheobronchial Diseases
Squamous-Cell Carcinoma of the Lung- ...Physical examination revealed decreased air entry in the base of the
Carcinoma of the Lung ... biopsy confirmed a diagnosis ... indicated stage IV disease ... #NEJM #clinical ... #radiology #CT #
Thumbprinting in Ischemic Colitis- Contrast-enhanced computed tomography of the abdomen, performed to evaluate the possibility of
complicated diverticular disease ... inflammatory bowel disease ... consistent with a diagnosis ... #radiology #CT ... thumbprinting #sign #NEJM
Pyoderma Gangrenosum in Ulcerative Colitis- ...left chest (Panel A) and leg (Panel B). The physical examination
A diagnosis of pyoderma ... underlying systemic disease ... inflammatory bowel disease ... #clinical #photo ... #NEJM #pyoderma
Lichen Planus- ...On examination, numerous purple papules were noted on the anterior surface of the forearms
confirming the diagnosis ... an autoimmune disease ... #NEJM #clinical ... lichen #planus #derm