17 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... Clinical history ... biliary, renal, lung ... concentration PET-CT ... increased IgG4+ cells
Plain radiography of the abdomen revealed calcification of both adrenal glands. A homozygous mutation in LIPA
confirmed the diagnosis ... deficiency, or Wolman’s disease ... #clincial #peds ... calcifications #infant #NEJM ... Wolmans #radiology #xray
Whistling Cough- A 4-year-old boy presented to the otorhinolaryngology outpatient clinic with a 2-day history of
otorhinolaryngology outpatient clinic ... and lower left lung ... child remained well ... #NEJM #clinical ... radiology #chest #xray
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... to 8 years Clinical ... • Chronic lung ... lymphocytic interstitial lung ... Chest CT: • Ground-glass
Echinococcal Cysts in the Liver- The physical examination revealed hepatomegaly with a palpable hepatic mass. Laboratory
a normal white-cell ... Hydatid disease ... #clinical #NEJM ... hepatic #radiology #CT
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Advanced HIV (CD4 cell ... : Clinical Manifestations ... Lung Disease: ... • Clinical (Symptoms ... Imaging, high res CT
Laryngocele- ...On physical examination, he had nontender, compressible swelling in the left cervical region that transmitted
A diagnosis of laryngocele ... which showed a well-defined ... #NEJM #clinical ... laryngoscope #radiology #CT
Squamous-Cell Carcinoma of the Lung- ...Physical examination revealed decreased air entry in the base of the
Squamous-Cell Carcinoma ... biopsy confirmed a diagnosis ... indicated stage IV disease ... #NEJM #clinical ... #radiology #CT #
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... (GCA) Giant cell ... Diagnosis = clinical ... in literature (NEJM ... cases (Cornelia NEJM
Esophageal Atresia and Tracheoesophageal Fistula- An infant had an apneic episode at birth and received positive-pressure
fistula, type C, was diagnosed ... and developing well ... #NEJM #clinical ... type #C #chest #Xray