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diagnosis management differential signs infections infectiousdiseases workup aids arteritis arthritis autoimmune bronchiectasis cell disease fungal gca giantcell histiocytosis hiv igg4
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... head and neck, pancreas ... biliary, renal, lung ... concentration PET-CT ... #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune disease ... and Symptoms: ... (interstitial lung ... disease), PAH ( ... Scleroderma #SSc #rheumatology
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... Nasal polyps and signs ... in the adjacent lung ... high-resolution chest CT ... mycobacteria Treatment
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Other tests: • CT ... or serologies + symptoms ... sparing of the lung ... seen on chest CT ... diagnosis #management #treatment
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Diagnosis Framework Disease ... angioinvasive disease ... • CT: Halo sign ... Constitutional symptoms ... Infections #HIV #AIDS #pulmonary
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Rheumatoid Arthritis - Signs ... and Symptoms • ... Scleromalacia perforans • Pulmonary ... : Parenchymal lung ... #rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
symptoms • Rheumatologic ... extrapulmonary disease ... or meningitic disease ... change in the lungs ... nails, bronchi, lungs
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... in literature (NEJM ... Treatment of GCA ... day, followed by long ... them, but urgent rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... , pancreas, stomach ... , pancreas, stomach
Langerhans Cell Histiocytosis (LCH) Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
• Pulmonary Symptoms ... Lungs: Cysts (esp ... Imaging: X-rays, CT ... PET-CT / MRI: Staging ... TREATMENT OPTIONS
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