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diagnosis management hematology syndrome activation alopecia antinxp2 antinxp2dm behcet cll dermatomyositis differential hair hairloss leukemia loss lymphocytic lymphohistiocytosis macrophage mas
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... age, however the disease ... signs and symptoms ... #Hemophagocytic ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
A subset of hemophagocytic ... lymphohistiocytosis (HLH ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Capitis - Skin Disease ... Examination: • Signs ... Prolactin, FSH, LH ... weight loss • Chronic ... Differential #Diagnosis #dermatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
common in Asia • HLA-B51 ... Arthritis, AS Treatment ... Recurrent and chronic ... diagnosis #management #signs ... #symptoms #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Physical Exam/Signs ... cells can indicate disease ... microglobulin Treatment ... workup #oncology #hematology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... shoulders (in a shawl sign ... had more severe disease ... positive patients Treatment ... #dermatology
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