30 results
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Primary Causes ... Creatinine & BUN: • Chronic ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #dermatology #Differential
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
Diagnosis Algorithm ... • Loose anagen syndrome ... to Skin Disease ... #dermatology #Differential ... #causes
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
to Systemic Diseases ... #Secondary #dermatology ... #Differential # ... Diagnosis #Algorithm ... #causes
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Allopecia - Differential ... , Loose anagen syndrome ... Vitamin D levels Systemic ... weight loss • Chronic ... Diagnosis #dermatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... • MPGN: Paraneoplastic ... cells can indicate disease ... microglobulin Treatment ... workup #oncology #hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... Myelodisplastic syndrome ... #systemic #generalized ... #dermatology #Differential ... #causes
Interstitial Lung Diseases (ILD)
Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): 
 • Hypersensitivity pneumonitis, Farmer's lung, Bird
: • Systemic sclerosis ... Churg Strauss syndrome ... #ILD #diagnosis ... #differential # ... pulmonary #causes
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... bone marrow and secondary ... -> Invade Skin: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
characterized by a systemic ... Skin rash and malaise ... #Rash #Diagnosis ... #Clinical #Photo ... #Dermatology
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
Diagnosis Framework ... into a 4-pass system ... : • Mast cell ... activation syndrome ... #Diagnosis #hematology