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diagnosis hematology causes differential hypertension leukemia management mds anemia aplastic cd4 chronic cll icl idiopathic indications lymphocytic lymphocytopenia lymphopenia myelodysplasia
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Syndrome (MD) - ... #Syndrome #MDS ... Management #treatment #hematology ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic ... formed or don’t work ... DDX: Rule Out Secondary ... Workup: • Complete ... #hematology #oncology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Differential Diagnosis Secondary ... vera (PV) • Myelodysplastic ... syndrome • Myelofibrosis ... Diagnosis #Causes #hematology ... #secondary
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... • Hypocellular myelodysplastic ... syndrome (MDS) ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing Common causes: • Renal parenchymal disease
Causes of Secondary ... • Cushing’s syndrome ... Acromegaly #Secondary ... Causes #Screening #Workup ... #table
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
Causes of Secondary ... Hypertension - Workup ... with previously stable ... Jcortesizaguirr #Secondary ... #Hypertension #Workup
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Richter’s Syndrome ... leukemia • Sezary syndrome ... Leukemia #diagnosis #workup ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... • Tumor lysis syndrome ... bone marrow and secondary ... #Leukemia #Hematology ... #Oncology #Diagnosis
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
underlying primary or secondary ... chemotherapy) • Genetic syndromes ... lymphoma. aplasia/myelodysplasia ... ICL #diagnosis #hematology
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